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Study Title and Description

Markers of dietary fat quality and fatty acid desaturation as predictors of total and cardiovascular mortality: a population-based prospective study.



Key Questions Addressed
2 Observational studies (longitudinal; quantile or continuous analysis)
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Primary Publication Information
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TitleData
Title Markers of dietary fat quality and fatty acid desaturation as predictors of total and cardiovascular mortality: a population-based prospective study.
Author Warensjö E., Sundström J., Vessby B., Cederholm T., Risérus U.
Country Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden.
Year 2008
Numbers Pubmed ID: 18614742
338 (internal)

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Observational Studies
Design Details
Question... Follow Up Answer Follow-up Answer
Study Design Observational: Prospective, longitudinal study of intake (eg, FFQ, biomarker)
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What is the name of this study? (e.g. DART, Physician's Health Study) ULSAM
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Country in which study conducted (where subjects live) Sweden
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Funding source No Data on funding or affiliations
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Eligibility Criteria: all men born between 1920 and 1924 living in Uppsala at that time.
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Study Population Primary Prevention, Healthy
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Conflict of interest No Data regarding conflict of interest
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Does the study report a subgroup or predictor (regression) analysis for an outcome of interest? No
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What type(s) of analysis is/are reported? Baseline biomarker level vs. outcomes
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Quantiles of baseline measures
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Continuous baseline measure
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Study start date(s) 1970
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Male, percent 100
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Race nd
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Baseline characteristics, continuous nd
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skip
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nd
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nd
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nd
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6.9
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1.3
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nd
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nd
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nd
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25.0
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skip
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3.2
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nd
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Baseline Diseases/Conditions 5
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43
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n3 Source Diet (Total)
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Results & Comparisons

No Results found.

Quality Dimensions
Dimension Value Notes Comments
Selection bias (NOT NESTED CASE CONTROL): Is there clear demonstration that the outcome of interest was not present at the start of the study (baseline)? Yes
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Comparability/Adjustment (ALL OBSERVATIONAL STUDIES): Were the analyses adjusted for confounders (or other factors)? Yes Including diet and CVD risk factors
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Outcome assessment (ALL STUDIES): Were OUTCOME ASSESSORS adequately BLINDED? Yes
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Incomplete outcome data (attrition bias) due to amount, nature or handling of incomplete outcome data (ALL STUDIES) low
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Nutrition, FFQ Baseline intake: Was the dietary assessment instrument (eg, FFQ) described to have measured n-3 FA (ALL STUDIES WITH FFQ)? Not Applicable biomarker-serum
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Nutrition, Baseline data: Were the ranges or distributions of the nutrient exposures adequately reported (ie, quantile means/medians SD and/or ranges) (ALL OBSERVATIONAL STUDIES)? Yes
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Additional Bias: Bias due to problems not covered elsewhere in the table. No
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Do any specific outcomes have a high risk of bias (different than others)? If so, describe in Notes. No
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Quality Rating
No quality rating data was found.