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Study Title and Description

The association between dietary omega-3 fatty acids and cardiovascular death: the Singapore Chinese Health Study.



Key Questions Addressed
2 Observational studies (longitudinal; quantile or continuous analysis)
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Primary Publication Information
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TitleData
Title The association between dietary omega-3 fatty acids and cardiovascular death: the Singapore Chinese Health Study.
Author Angela S Koh, An Pan, Renwei Wang, Andrew O Odegaard, Mark A Pereira, Jian-Min Yuan, Woon-Puay Koh
Country -- Not Found --
Year 2013
Numbers Pubmed ID: 24343844

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Observational Studies
Design Details
Question... Follow Up Answer Follow-up Answer
Study Design Observational: Prospective, longitudinal study of intake (eg, FFQ, biomarker)
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What is the name of this study? (e.g. DART, Physician's Health Study) The Singapore Chinese Health Study
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Country in which study conducted (where subjects live) ... Specify Other(s) [Separate countries with commas]: ... Singapore, China
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Funding source No industry relationship reported (funding or affiliations reported)
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Eligibility Criteria: We excluded individuals who had baseline cancer (n = 1936) or reported extreme energy intakes (<600 or >3000 kcal/day for women and <700 or >3700 kcal/day for men; n = 1023).
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Study Population Primary Prevention, Healthy
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At baseline, did all subjects have (per eligibility criteria)...? Diabetes and/or metabolic syndrome*
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Hypertension ...
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Cardiac disease ...
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Cerebrovascular disease ...
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Arrhythmia ...
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Conflict of interest No conflict of interest (explicitly stated)
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Does the study report a subgroup or predictor (regression) analysis for an outcome of interest? ... Which subgroups/predictors? Yes ... prior history of CHD or stroke
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What type(s) of analysis is/are reported? Quantiles of baseline measures
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Study start date(s) 1993
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Male, percent 27954, 44.2%
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Race 100
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Chinese
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Baseline characteristics, continuous 56
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23.2
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3.3
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47, 74
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Baseline Diseases/Conditions 8.9%
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23.7%
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1.1%
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n3 Source Fish diet
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Plant diet (ALA)
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Diet (Total)
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Results & Comparisons

No Results found.

Quality Dimensions
Dimension Value Notes Comments
Selection bias (NOT NESTED CASE CONTROL): Is there clear demonstration that the outcome of interest was not present at the start of the study (baseline)? Yes
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Comparability/Adjustment (ALL OBSERVATIONAL STUDIES): Were the analyses adjusted for confounders (or other factors)? Yes Including diet and CVD risk factors (eg, lipids, BP, DM)
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Outcome assessment (ALL STUDIES): Were OUTCOME ASSESSORS adequately BLINDED? UNCLEAR
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Incomplete outcome data (attrition bias) due to amount, nature or handling of incomplete outcome data (ALL STUDIES) LOW
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Nutrition, FFQ Baseline intake: Was the dietary assessment instrument (eg, FFQ) described to have measured n-3 FA (ALL STUDIES WITH FFQ)? No No data on instrument or method used to measure n-3 FA intake
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Nutrition, Baseline data: Were the ranges or distributions of the nutrient exposures adequately reported (ie, quantile means/medians SD and/or ranges) (ALL OBSERVATIONAL STUDIES)? No
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Additional Bias: Bias due to problems not covered elsewhere in the table. No
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Do any specific outcomes have a high risk of bias (different than others)? If so, describe in Notes. No
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Quality Rating
No quality rating data was found.