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Study Title and Description

The effect of aspartame as part of a multidisciplinary weight-control program on short- and long-term control of body weight.



Key Questions Addressed
1 What is the relationship between low-calorie sweeteners and body weight and composition in randomized controlled studies?
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Primary Publication Information
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TitleData
Title The effect of aspartame as part of a multidisciplinary weight-control program on short- and long-term control of body weight.
Author Blackburn GL., Kanders BS., Lavin PT., Keller SD., Whatley J.
Country Center for the Study of Nutrition Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Year 1997
Numbers Pubmed ID: 9022524
13290 (internal)

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Extraction form for randomized controlled trials
Arms
No arms have been defined in this extraction form.

Design Details
Question... Follow Up Answer Follow-up Answer
Author, year Blackburn, 1997
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Country US
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Baseline age range (y) or mean (SD) 20-60
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Children, Adolescents, or Adults Adults
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Other population characteristics Obese, sedentary, but otherwise healthy
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Baseline BMI (mean) 37.3
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Intervention details 1: Active weight-loss diet (1000 + 200 kcal); assigned to aspartame-sweetened or sucrose-sweetened foods and drinks; exercise program provided; weekly sessions with RD 2: 1-y weight-maintenance program (1500 + 300 kcal) following active weight-loss period; participants encouraged or discouraged from using aspartame-sweetened products according to original assignment in active weight loss phase; exercise program provided; group sessions with RD
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Tx arm 1: aspartame-sweetened pudding, milk shakes, and noncarbonated beverage mix, and packets of tabletop sweetener 2: encouraged to use aspartame-sweetened products (according to original assignment in active weight loss phase); provided with diet instructions and exercise program
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Beverage (B), Food (F), or Supplement (S) 1: BFS 2: BFS
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Weight loss diet in tx? 1: Y 2: N
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Control arm 1: diet with sucrose-sweetened items (conventional diet); sucrose-sweetened items included soda, fruit-flavored drinks, puddings, gelatins, ice cream, frozen fruits in syrup, jam, pancake syrup, powdered table top sweetener 2: discouraged from using aspartame-sweetened products (according to original assignment in active weight loss phase); provided with diet instructions and exercise program
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Weight loss diet in control? 1: Y 2: N
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Energy intake significantly less in tx? 1: N 2: N
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Duration (wk) 1: 16 2: 52
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No. analyzed (tx) 1: 71 2: 61
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No. analyzed (control) 1: 65 2: 64
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Intake of sweetener (tx) mean (SD) 1: 285 (235) aspartame 2: 279 (178) aspartame
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Sex (M, F) 1: 136 F 2: 125 F
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Outcome measure 1 Body weight (kg)
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Outcome measure 2
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Outcome measure 3
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Outcome measure 4
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Pre-study mean outcome 1 (tx) NA
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Pre-study mean outcome 2 (tx)
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Pre-study mean outcome 3 (tx)
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Pre-study mean outcome 4 (tx)
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Pre-study SD outcome 1 (tx) NA
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Pre-study SD outcome 2 (tx)
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Pre-study SD outcome 3 (tx)
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Pre-study SD outcome 4 (tx)
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Post-study mean outcome 1 (tx) NA
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Post-study mean outcome 2 (tx)
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Post-study mean outcome 3 (tx)
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Post-study mean outcome 4 (tx)
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Post-study SD outcome 1 (tx) NA
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Post-study SD outcome 2 (tx)
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Post-study SD outcome 3 (tx)
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Post-study SD outcome 4 (tx)
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Pre-study mean outcome 1 (control) NA
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Pre-study mean outcome 2 (control)
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Pre-study mean outcome 3 (control)
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Pre-study mean outcome 4 (control)
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Pre-study SD outcome 1 (control) NA
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Pre-study SD outcome 2 (control)
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Pre-study SD outcome 3 (control)
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Pre-study SD outcome 4 (control)
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Post-study mean outcome 1 (control) NA
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Post-study mean outcome 2 (control)
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Post-study mean outcome 3 (control)
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Post-study mean outcome 4 (control)
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Post-study SD outcome 1 (control) NA
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Post-study SD outcome 2 (control)
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Post-study SD outcome 3 (control)
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Post-study SD outcome 4 (control)
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Mean change outcome 1 (tx) 1: -9.90 2: 2.60
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Mean change outcome 2 (tx)
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Mean change outcome 3 (tx)
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Change SD outcome 1 (tx) 1: 6.10 2: 9.46
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Change SD outcome 2 (tx)
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Change SD outcome 3 (tx)
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Mean change outcome 1 (control) 1: -9.80 2: 5.40
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Mean change outcome 2 (control)
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Mean change outcome 3 (control)
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Change SD outcome 1 (control) 1: 6.50 2: 9.50
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Change SD outcome 2 (control)
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Change SD outcome 3 (control)
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Notes
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Baseline Characteristics
No baseline characteristics have been defined for this extraction form.



Results & Comparisons

No Results found.
Adverse Events
Arm or Total Title Description Comments

Quality Dimensions
No quality dimensions were specified.

Quality Rating
No quality rating data was found.