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Study Title and Description

Effects of aspartame in young persons during weight reduction.



Key Questions Addressed
1 What is the relationship between low-calorie sweeteners and body weight and composition in randomized controlled studies?
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Primary Publication Information
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TitleData
Title Effects of aspartame in young persons during weight reduction.
Author Knopp RH., Brandt K., Arky RA.
Country -- Not Found --
Year 1976
Numbers Pubmed ID: 796476
13297 (internal)

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Extraction form for randomized controlled trials
Arms
No arms have been defined in this extraction form.

Design Details
Question... Follow Up Answer Follow-up Answer
Author, year Knopp, 1976
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Country US
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Baseline age range (y) or mean (SD) 10-21
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Children, Adolescents, or Adults Children/ adolescents
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Other population characteristics Most recruited from nursing schools; others were pediatric obesity referrals
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Baseline BMI (mean) NR; overweight on average
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Intervention details participants randomized to aspartame or lactose gelatin capsules; both groups were provided instructions by RD on calorie-restricted diet
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Tx arm 3x300 mg capsules aspartame in addition to calorie-restricted diet instructions by RD
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Beverage (B), Food (F), or Supplement (S) S
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Weight loss diet in tx? Y
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Control arm 3x300 mg capsules lactose in addition to calorie-restricted diet instructions by RD
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Weight loss diet in control? Y
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Energy intake significantly less in tx? N
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Duration (wk) 13
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No. analyzed (tx) 24
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No. analyzed (control) 33
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Intake of sweetener (tx) mean (SD) 2.7 g/d aspartame
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Sex (M, F) 4 M, 51 F
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Outcome measure 1 Body weight (kg)
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Outcome measure 2
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Outcome measure 3
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Outcome measure 4
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Pre-study mean outcome 1 (tx) NA
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Pre-study mean outcome 2 (tx)
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Pre-study mean outcome 3 (tx)
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Pre-study mean outcome 4 (tx)
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Pre-study SD outcome 1 (tx) NA
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Pre-study SD outcome 2 (tx)
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Pre-study SD outcome 3 (tx)
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Pre-study SD outcome 4 (tx)
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Post-study mean outcome 1 (tx) NA
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Post-study mean outcome 2 (tx)
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Post-study mean outcome 3 (tx)
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Post-study mean outcome 4 (tx)
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Post-study SD outcome 1 (tx) NA
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Post-study SD outcome 2 (tx)
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Post-study SD outcome 3 (tx)
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Post-study SD outcome 4 (tx)
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Pre-study mean outcome 1 (control) NA
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Pre-study mean outcome 2 (control)
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Pre-study mean outcome 3 (control)
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Pre-study mean outcome 4 (control)
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Pre-study SD outcome 1 (control) NA
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Pre-study SD outcome 2 (control)
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Pre-study SD outcome 3 (control)
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Pre-study SD outcome 4 (control)
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Post-study mean outcome 1 (control) NA
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Post-study mean outcome 2 (control)
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Post-study mean outcome 3 (control)
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Post-study mean outcome 4 (control)
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Post-study SD outcome 1 (control) NA
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Post-study SD outcome 2 (control)
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Post-study SD outcome 3 (control)
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Post-study SD outcome 4 (control)
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Mean change outcome 1 (tx) -3.14
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Mean change outcome 2 (tx)
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Mean change outcome 3 (tx)
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Change SD outcome 1 (tx) 0.68
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Change SD outcome 2 (tx)
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Change SD outcome 3 (tx)
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Mean change outcome 1 (control) -2.05
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Mean change outcome 2 (control)
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Mean change outcome 3 (control)
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Change SD outcome 1 (control) 0.55
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Change SD outcome 2 (control)
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Change SD outcome 3 (control)
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Notes
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Baseline Characteristics
No baseline characteristics have been defined for this extraction form.



Results & Comparisons

No Results found.
Adverse Events
Arm or Total Title Description Comments

Quality Dimensions
No quality dimensions were specified.

Quality Rating
No quality rating data was found.