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Study Title and Description

Sucrose-sweetened beverages increase fat storage in the liver, muscle, and visceral fat depot: a 6-mo randomized intervention study.



Key Questions Addressed
1 What is the relationship between low-calorie sweeteners and body weight and composition in randomized controlled studies?
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Primary Publication Information
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TitleData
Title Sucrose-sweetened beverages increase fat storage in the liver, muscle, and visceral fat depot: a 6-mo randomized intervention study.
Author Maersk M., Belza A., Stødkilde-Jørgensen H., Ringgaard S., Chabanova E., Thomsen H., Pedersen SB., Astrup A., Richelsen B.
Country Department of Endocrinology and Internal Medicine MEA, Aarhus University Hospital, Denmark.
Year 2012
Numbers Pubmed ID: 22205311
13298 (internal)

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Extraction form for randomized controlled trials
Arms
No arms have been defined in this extraction form.

Design Details
Question... Follow Up Answer Follow-up Answer
Author, year Maersk, 2012
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Country Denmark
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Baseline age range (y) or mean (SD) 20-50
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Children, Adolescents, or Adults Adults
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Other population characteristics Overweight/ obese [BMI between 26-40)]
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Baseline BMI (mean) 32.1
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Intervention details Participants randomly assigned to one of 4 drinks (1 L/d): sucrose-sweetened soft drink (regular cola), isocaloric semiskim milk, aspartame-sweetened diet cola, or water
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Tx arm Participants received batches of aspartame-sweetened soda 2-3 times per mo to consume 1 L/d
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Beverage (B), Food (F), or Supplement (S) B
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Weight loss diet in tx? N
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Control arm 1: Participants received batches of sucrose-sweetened soda 2-3 times per mo to consume 1 L/d 2: Participants received batches of semi-skim milk 2-3 times per mo to consume 1 L/d 3: Participants received batches of water 2-3 times per mo to consume 1 L/d
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Weight loss diet in control? N
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Energy intake significantly less in tx? NR
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Duration (wk) 26
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No. analyzed (tx) 12
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No. analyzed (control) 10
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Intake of sweetener (tx) mean (SD) 33.8 oz/d aspartame diet soda
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Sex (M, F) 17 M, 30 F
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Outcome measure 1 Body weight (kg)
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Outcome measure 2 Fat mass (kg)
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Outcome measure 3
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Outcome measure 4
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Pre-study mean outcome 1 (tx) NA
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Pre-study mean outcome 2 (tx) NA
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Pre-study mean outcome 3 (tx)
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Pre-study mean outcome 4 (tx)
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Pre-study SD outcome 1 (tx) NA
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Pre-study SD outcome 2 (tx) NA
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Pre-study SD outcome 3 (tx)
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Pre-study SD outcome 4 (tx)
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Post-study mean outcome 1 (tx) NA
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Post-study mean outcome 2 (tx) NA
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Post-study mean outcome 3 (tx)
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Post-study mean outcome 4 (tx)
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Post-study SD outcome 1 (tx) NA
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Post-study SD outcome 2 (tx) NA
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Post-study SD outcome 3 (tx)
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Post-study SD outcome 4 (tx)
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Pre-study mean outcome 1 (control) NA
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Pre-study mean outcome 2 (control) NA
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Pre-study mean outcome 3 (control)
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Pre-study mean outcome 4 (control)
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Pre-study SD outcome 1 (control) NA
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Pre-study SD outcome 2 (control) NA
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Pre-study SD outcome 3 (control)
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Pre-study SD outcome 4 (control)
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Post-study mean outcome 1 (control) NA
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Post-study mean outcome 2 (control) NA
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Post-study mean outcome 3 (control)
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Post-study mean outcome 4 (control)
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Post-study SD outcome 1 (control) NA
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Post-study SD outcome 2 (control) NA
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Post-study SD outcome 3 (control)
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Post-study SD outcome 4 (control)
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Mean change outcome 1 (tx) 1, 2, 3: 0.11
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Mean change outcome 2 (tx) 1, 2, 3: -0.18
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Mean change outcome 3 (tx)
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Change SD outcome 1 (tx) 1, 2, 3: 3.51
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Change SD outcome 2 (tx) 1, 2, 3: 3.04
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Change SD outcome 3 (tx)
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Mean change outcome 1 (control) 1: 1.25 2: 1.28 3: 0.59
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Mean change outcome 2 (control) 1: 1.07 2: 0.50 3: 0.18
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Mean change outcome 3 (control)
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Change SD outcome 1 (control) 1: 3.40 2: 3.61 3: 3.67
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Change SD outcome 2 (control) 1: 2.90 2: 3.07 3: 3.49
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Change SD outcome 3 (control)
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Notes
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Baseline Characteristics
No baseline characteristics have been defined for this extraction form.



Results & Comparisons

No Results found.
Adverse Events
Arm or Total Title Description Comments

Quality Dimensions
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