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Study Title and Description

Long-term dietary compensation for added sugar: effects of supplementary sucrose drinks over a 4-week period.



Key Questions Addressed
1 What is the relationship between low-calorie sweeteners and body weight and composition in randomized controlled studies?
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Primary Publication Information
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TitleData
Title Long-term dietary compensation for added sugar: effects of supplementary sucrose drinks over a 4-week period.
Author Reid M., Hammersley R., Hill AJ., Skidmore P.
Country Psychology Department, Queen Margaret University College, Edinburgh, UK. mreid@qmuc.ac.uk
Year 2007
Numbers Pubmed ID: 17217576
13301 (internal)

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Extraction form for randomized controlled trials
Arms
No arms have been defined in this extraction form.

Design Details
Question... Follow Up Answer Follow-up Answer
Author, year Reid, 2007
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Country UK
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Baseline age range (y) or mean (SD) 20-55
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Children, Adolescents, or Adults Adults
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Other population characteristics Generally healthy, non-pregnant/ non-lactating normal-weight women
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Baseline BMI (mean) 22.5
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Intervention details participants received soft drinks [4x250 mL bottles of IRN-BRU (soda)/d totalling 34 oz] sweetened with either sucrose or aspartame; some were
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Tx arm 34 oz diet soda (acesulfame K + aspartame) provided in 4 uniform color bottles
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Beverage (B), Food (F), or Supplement (S) B
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Weight loss diet in tx? N
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Control arm 34 oz sucrose-sweetened soda provided in 4 uniform bottles
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Weight loss diet in control? N
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Energy intake significantly less in tx? Y
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Duration (wk) 4
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No. analyzed (tx) 65
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No. analyzed (control) 68
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Intake of sweetener (tx) mean (SD) 34 oz/d artificially sweetened soda (aspartame + acesulfame K)
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Sex (M, F) 133 F
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Outcome measure 1 Body weight (kg)
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Outcome measure 2 BMI
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Outcome measure 3
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Outcome measure 4
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Pre-study mean outcome 1 (tx) 21.99
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Pre-study mean outcome 2 (tx) NA
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Pre-study mean outcome 3 (tx)
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Pre-study mean outcome 4 (tx)
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Pre-study SD outcome 1 (tx) 2.66
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Pre-study SD outcome 2 (tx) NA
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Pre-study SD outcome 3 (tx)
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Pre-study SD outcome 4 (tx)
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Post-study mean outcome 1 (tx) 21.9
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Post-study mean outcome 2 (tx) NA
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Post-study mean outcome 3 (tx)
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Post-study mean outcome 4 (tx)
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Post-study SD outcome 1 (tx) 2.77
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Post-study SD outcome 2 (tx) NA
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Post-study SD outcome 3 (tx)
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Post-study SD outcome 4 (tx)
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Pre-study mean outcome 1 (control) 22.76
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Pre-study mean outcome 2 (control) NA
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Pre-study mean outcome 3 (control)
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Pre-study mean outcome 4 (control)
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Pre-study SD outcome 1 (control) 2.88
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Pre-study SD outcome 2 (control) NA
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Pre-study SD outcome 3 (control)
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Pre-study SD outcome 4 (control)
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Post-study mean outcome 1 (control) 22.87
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Post-study mean outcome 2 (control) NA
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Post-study mean outcome 3 (control)
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Post-study mean outcome 4 (control)
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Post-study SD outcome 1 (control) 2.98
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Post-study SD outcome 2 (control) NA
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Post-study SD outcome 3 (control)
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Post-study SD outcome 4 (control)
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Mean change outcome 1 (tx) NA
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Mean change outcome 2 (tx) 0.29
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Mean change outcome 3 (tx)
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Change SD outcome 1 (tx) NA
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Change SD outcome 2 (tx) 1.08
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Change SD outcome 3 (tx)
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Mean change outcome 1 (control) NA
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Mean change outcome 2 (control) -0.3
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Mean change outcome 3 (control)
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Change SD outcome 1 (control) NA
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Change SD outcome 2 (control) 1.21
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Change SD outcome 3 (control)
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Notes Used Plot Digitizer to obtain body weight outcome data from Figure 3, then generated means +/- SDs
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Baseline Characteristics
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Results & Comparisons

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Adverse Events
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