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Study Title and Description

Sugar-sweetened beverages, weight gain, and incidence of type 2 diabetes in young and middle-aged women.



Key Questions Addressed
2 What is the relationship between low-calorie sweeteners and body weight and composition in prospective observational cohort studies?
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Primary Publication Information
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TitleData
Title Sugar-sweetened beverages, weight gain, and incidence of type 2 diabetes in young and middle-aged women.
Author Schulze MB., Manson JE., Ludwig DS., Colditz GA., Stampfer MJ., Willett WC., Hu FB.
Country Department of Nutrition, Harvard School of Public Health, Boston, Mass, USA. mschulze@channing.harvard.edu
Year 2004
Numbers Pubmed ID: 15328324
13313 (internal)

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Extraction form for prospective observational studies
Arms
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Design Details
Question... Follow Up Answer Follow-up Answer
Author, year Schulze, 2004
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Cohort name NHS II
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Country US
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Baseline age, y 24-44
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Follow-up, y (between diet and outcome) 4
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Children/ adolescents (C) or adults (A) A
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Other population characteristics Registered nurses, generally healthy (no T2D, cancer, CVD at baseline)
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Mean BMI 24.5
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Author-defined exposure Change in diet soft drink consumption (low-calorie soda and other low-calorie beverages) from <= 1 drink/wk to >=1 drink/d or >=drink/d to <=1 drink/wk
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Assigned exposure LCS beverage intake
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Beverage (B), Food (F), or Supplement (S) B
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Exposure assessment method FFQ
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Diet assessment method 3 questions on validated FFQ
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Year diet assessed 1991-99
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Analytic cohort no. 51603
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Sex (M, F) 51603 F
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Author-defined outcome 1 Weight gain
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Author-defined outcome 2
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Assigned outcome 1 BW change
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Assigned outcome 2
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Exposure unit servings/d
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β1 for Δ in outcome per unit increase in baseline exposure NA
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β2 for Δ in outcome per unit increase in baseline exposure
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SE1 for β (baseline exposure) NA
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SE2 for β (baseline exposure)
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t-statistic (baseline exposure and outcome) NA
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β for Δ in outcome per unit change in exposure overtime NA
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SE for β (change in exposure overtime) NA
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t-statistic (baseline exposure and outcome overtime) NA
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Quantiles NR
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Q1 intake
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Highest Q intake >1
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Q1 change in outcome 4.25
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Q1 SD change in outcome 14.53
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Highest Q mean change in outcome 1.59
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Highest Q SD change in outcome 17.17
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RR (highest vs. lowest) NA
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LL (highest vs. lowest) NA
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UL (highest vs. lowest) NA
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Dose-response RR NA
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Dose-response LL NA
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Dose-response UL NA
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Statistical adjustments age, alcohol intake, postmenopausal hormone use, oral contraceptive use, cereal fiber intake, total fat intake, BMI, PA, smoking,
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MV-adjusted (Y/N) Y
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Energy-adjusted (Y/N) N
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Baseline BMI/ weight-adjusted Y
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Notes Cohort followed for 8y but 4y changes in weight were examined; the results represent the weight change associated with moving from >1 to 1 serving/d (+1.59 kg)
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Baseline Characteristics
No baseline characteristics have been defined for this extraction form.



Results & Comparisons

No Results found.
Adverse Events
Arm or Total Title Description Comments

Quality Dimensions
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Quality Rating
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