Advanced Search

Study Preview



Study Title and Description

Long-term blood cholesterol-lowering effects of a dietary fiber supplement.



Key Questions Addressed
1 Is this a fiber intervention study?
  • Comments Comments (
    0
    ) |

Primary Publication Information
  • Comments Comments (
    0
    ) |
TitleData
Title Long-term blood cholesterol-lowering effects of a dietary fiber supplement.
Author Knopp RH., Superko HR., Davidson M., Insull W., Dujovne CA., Kwiterovich PO., Zavoral JH., Graham K., O'Connor RR., Edelman DA.
Country N.W. Lipid Research Clinic, Harborview Medical Center, Seattle, Washington, USA.
Year 1999
Numbers Pubmed ID: 10429748

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Fiber Database
Arms
No arms have been defined in this extraction form.

Design Details
Question... Follow Up Answer Follow-up Answer
Year of Publication 1999
  • Comments Comments (
    0
    ) |
Country of Publication United States
  • Comments Comments (
    0
    ) |
What was the study design? Randomized Controlled Trial (parallel)
  • Comments Comments (
    0
    ) |
Was the study blinded? double blind
  • Comments Comments (
    0
    ) |
Study diet type Unspecified
  • Comments Comments (
    0
    ) |
Level of feeding control for dietary intervention partial metabolic study; participants were advised to follow the National Cholesterol Education Program (NCEP) Step 1 Diet; during the extension phase those receiving the placebo were given the fiber supplement
  • Comments Comments (
    0
    ) |
Sample size 169
  • Comments Comments (
    0
    ) |
Is there a run-in period? Yes
  • Comments Comments (
    0
    ) |
Is there a washout period? No
  • Comments Comments (
    0
    ) |
Did the administered fiber dose change over the course of the study? No
  • Comments Comments (
    0
    ) |
What is the age of the population (categorical)? Adults (20+ Years)
  • Comments Comments (
    0
    ) |
Study population, mean age in years ~52.4
  • Comments Comments (
    0
    ) |
Study population, age range in years 29-69
  • Comments Comments (
    0
    ) |
Study Population, mean BMI, kg/m2 ~25.7
  • Comments Comments (
    0
    ) |
Study population, BMI Range, kg/m2 -
  • Comments Comments (
    0
    ) |
Baseline health status Healthy, Hyperlipidemia/hypercholesterolemia
  • Comments Comments (
    0
    ) |
Gender (% male) 64.2
  • Comments Comments (
    0
    ) |
Fiber 1-type Combination/Mixture
  • Comments Comments (
    0
    ) |
Fiber 1-if combination was selected for fiber type, 1st fiber type in combination Mixture of guar gum and pectin
  • Comments Comments (
    0
    ) |
Fiber 1-if combination was selected for fiber type, 2nd fiber type in combination Mixture of soy fiber, pea fiber, and corn bran
  • Comments Comments (
    0
    ) |
Fiber 1- dose 1 (g) 15.0
  • Comments Comments (
    0
    ) |
Fiber 1- dose 2 (g) 5.0
  • Comments Comments (
    0
    ) |
Fiber 1-Duration of intervention 15 weeks
  • Comments Comments (
    0
    ) |
Fiber 1-how was the fiber administered? Powder
  • Comments Comments (
    0
    ) |
Fiber 2-type -
  • Comments Comments (
    0
    ) |
Fiber 2-if combination was selected for fiber type, 1st fiber type in combination -
  • Comments Comments (
    0
    ) |
Fiber 2-if combination was selected for fiber type, 2nd fiber type in combination -
  • Comments Comments (
    0
    ) |
Fiber 2- dose 1 (g) -
  • Comments Comments (
    0
    ) |
Fiber 2- dose 2 (g) -
  • Comments Comments (
    0
    ) |
Fiber 2-Duration of intervention -
  • Comments Comments (
    0
    ) |
Fiber 2-how was the fiber administered? -
  • Comments Comments (
    0
    ) |
Fiber 3-type -
  • Comments Comments (
    0
    ) |
Fiber 3-if combination was selected for fiber type, 1st fiber type in combination -
  • Comments Comments (
    0
    ) |
Fiber 3-if combination was selected for fiber type, 2nd fiber type in combination -
  • Comments Comments (
    0
    ) |
Fiber 3- dose 1 (g) -
  • Comments Comments (
    0
    ) |
Fiber 3- dose 2 (g) -
  • Comments Comments (
    0
    ) |
Fiber 3-Duration of intervention -
  • Comments Comments (
    0
    ) |
Fiber 3-how was the fiber administered? -
  • Comments Comments (
    0
    ) |
Fiber 4-type -
  • Comments Comments (
    0
    ) |
Fiber 4-if combination was selected for fiber type, 1st fiber type in combination -
  • Comments Comments (
    0
    ) |
Fiber 4-if combination was selected for fiber type, 2nd fiber type in combination -
  • Comments Comments (
    0
    ) |
Fiber 4- dose 1 (g) -
  • Comments Comments (
    0
    ) |
Fiber 4- dose 2 (g) -
  • Comments Comments (
    0
    ) |
Fiber 4-Duration of intervention -
  • Comments Comments (
    0
    ) |
Fiber 4-how was the fiber administered? -
  • Comments Comments (
    0
    ) |
Comparator 1- what was the comparator used in the intervention? matched
  • Comments Comments (
    0
    ) |
Comparator 1-dose 0.0
  • Comments Comments (
    0
    ) |
Comparator 1-duration of comparator intervention 15 weeks
  • Comments Comments (
    0
    ) |
Comparator 1-how was the comparator administered to participants? Powder
  • Comments Comments (
    0
    ) |
Comparator 2- what was the comparator used in the intervention? -
  • Comments Comments (
    0
    ) |
Comparator 2-dose -
  • Comments Comments (
    0
    ) |
Comparator 2-duration of comparator intervention -
  • Comments Comments (
    0
    ) |
Comparator 2-how was the comparator administered to participants? -
  • Comments Comments (
    0
    ) |
Comparator 3- what was the comparator used in the intervention? -
  • Comments Comments (
    0
    ) |
Comparator 3-dose -
  • Comments Comments (
    0
    ) |
Comparator 3-duration of comparator intervention -
  • Comments Comments (
    0
    ) |
Comparator 3-how was the comparator administered to participants? -
  • Comments Comments (
    0
    ) |
Comparator 4- what was the comparator used in the intervention? -
  • Comments Comments (
    0
    ) |
Comparator 4-dose -
  • Comments Comments (
    0
    ) |
Comparator 4-duration of comparator intervention -
  • Comments Comments (
    0
    ) |
Comparator 4-how was the comparator administered to participants? -
  • Comments Comments (
    0
    ) |


Baseline Characteristics
No baseline characteristics have been defined for this extraction form.



Results & Comparisons

No Results found.
Adverse Events
Arm or Total Title Description Comments

Quality Dimensions
No quality dimensions were specified.

Quality Rating
No quality rating data was found.