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Study Title and Description

Effects on obese women of the sugar sucrose added to the diet over 28 d: a quasi-randomised, single-blind, controlled trial.



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title Effects on obese women of the sugar sucrose added to the diet over 28 d: a quasi-randomised, single-blind, controlled trial.
Author Reid M, Hammersley R, Duffy M, Ballantyne C.
Country Department of Psychology, University of Hull, Hull, UK.
Year 2014
Numbers Pubmed ID: 24164779

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure Aspartame
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Comparator Sucrose
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LCS vs sugar/ or others 1
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Outcomes predicted and observed end body weight (wk 4); mean daily macronutrient intake through the course of the experiment (g/d of total; carbohydrate; protein; fat and sugar) and mean comparisons by week; including and excluding the beverage supplement; Hunger and thirst were rated 4x/d as part of the mood rating procedure for each drink; and means per subject for weeks 1 and 4 were compared
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Study Design nRCT-p
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Country/Region US
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Age (mean or range) 34.9
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Age 34.9
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% Male 0
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BMI 32.8
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Intervention Form Beverage
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Sample size 41
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Number analyzed (intervention) 21
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Number analyzed (control) 20
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Baseline health obese
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Baseline health (coded) overweight
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Duration 4 weeks
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Duration (coded) 1 - 6 months
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brain 0
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glycaemia 0
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appetite 1
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dietary 1
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bodyweight 1
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Primary (Most important outcome) body weight
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Hypotheses/Aim(s) of Study The aim of the study was to determine the effects of sucrose beverages consumed over 4 weeks compared with a placebo containing artiļ¬cial sweeteners in obese women. All the participants were told they were being given sucrose-sweetened soft drinks, meaning that 1/2 of the participants were misinformed.,,The hypothesis was that obese women, similar to overweight and normal-weight women in previous studies, would partially compensate for the energy content of supplementary soft drinks and (1) not gain weight, (2) reduce energy intake elsewhere in the diet, (3) reduce the total fat content of the diet and (4) reduce the ad libitum CHO content of the diet (measured by the self-reported food intake in the food diaries)
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Funding source nr
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Funding(coded) nr
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Internal
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