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Study Title and Description

Differences in brain responses between lean and obese women to a sweetened drink.



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title Differences in brain responses between lean and obese women to a sweetened drink.
Author Connolly L, Coveleskie K, Kilpatrick LA, Labus JS, Ebrat B, Stains J, Jiang Z, Tillisch K, Raybould HE, Mayer EA.
Country Oppenheimer Family Center for Neurobiology of Stress, Los Angeles, CA 90095-7378, USA. emayer@ucla.edu
Year 2013
Numbers Pubmed ID: 23566308

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure Stevia
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Comparator Sucrose
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LCS vs sugar/ or others 1
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Outcomes Ratings on: taste of beverages; hunger/appetite; satisfaction; desire for sweetness; Results of fullness questionnaire (fullness; hunger; etc)
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Study Design RCT-c
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Country/Region US
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Age (mean or range) 25.6
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Age 25.6
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% Male 0
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BMI 27.7
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Intervention Form Beverage
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Sample size 20
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Number analyzed (intervention) 20
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Number analyzed (control) 20
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Baseline health mix of healthy and obese
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Baseline health (coded) Mixed
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Duration 1 day
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Duration (coded) <1 day
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brain 1
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glycaemia 0
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appetite 1
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dietary 0
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bodyweight 0
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Primary (Most important outcome) appetite
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Hypotheses/Aim(s) of Study aimed to test the following main hypotheses:,(i) Brain responses to the ingestion of a non-nutrient sweetened and a sucrose-sweetened drink will be similar, presumably involving similar engage-ment of sweet taste receptors; ,(ii) during visual food-related cues, obese subjects will show greater affective and/or hedonic brain and behavioral responses to sucrose compared with lean controls.
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Funding source NIH
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Funding(coded) Government
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Internal
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Results & Comparisons

No Results found.