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Study Title and Description

Effects of a D-xylose preload with or without sitagliptin on gastric emptying, glucagon-like peptide-1, and postprandial glycemia in type 2 diabetes.



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title Effects of a D-xylose preload with or without sitagliptin on gastric emptying, glucagon-like peptide-1, and postprandial glycemia in type 2 diabetes.
Author Wu T, Bound MJ, Zhao BR, Standfield SD, Bellon M, Jones KL, Horowitz M, Rayner CK.
Country Discipline of Medicine, University of Adelaide, Royal Adelaide Hospital, Adelaide, Australia.
Year 2013
Numbers Pubmed ID: 23359361

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure Sucralose
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Comparator D-xylose
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LCS vs sugar/ or others 2
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Outcomes Blood glucose; serum insulin; GLP-1; breath hydrogen production; gastric emptying
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Study Design RCT-c
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Country/Region AU
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Age (mean or range) 66.2
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Age 66.2
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% Male 0.75
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BMI 28.9
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Intervention Form Beverage
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Sample size 12
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Number analyzed (intervention) 12
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Number analyzed (control) 12
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Baseline health Diabetic
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Baseline health (coded) Diabetic
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Duration 12 days
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Duration (coded) 2 day - 1 month
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brain 0
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glycaemia 1
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appetite 0
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dietary 0
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bodyweight 0
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Primary (Most important outcome) glycaemia
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Hypotheses/Aim(s) of Study We hypothesized that "diet"beverages would empty from the stomach more rapidly,resulting in higher blood ethanol concentrations.
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Funding source Drug and Alcohol Resource, Royal Adelaide Hospital
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Funding(coded) Government
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Internal
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Results & Comparisons

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