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Study Title and Description

Satiety scores and satiety hormone response after sucrose-sweetened soft drink compared with isocaloric semi-skimmed milk and with non-caloric soft drink: a controlled trial.



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title Satiety scores and satiety hormone response after sucrose-sweetened soft drink compared with isocaloric semi-skimmed milk and with non-caloric soft drink: a controlled trial.
Author Maersk M, Belza A, Holst JJ, Fenger-Grøn M, Pedersen SB, Astrup A, Richelsen B.
Country Department of Internal Medicine and Endocrinology (MEA), Aarhus University Hospital, Aarhus C, Denmark.
Year 2012
Numbers Pubmed ID: 22252107

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure Aspartame
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Comparator regular cola; milk; water
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LCS vs sugar/ or others 1
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Outcomes Appetite hormone response: Grehlin; GLP-1; GIP; Insulin; glucose; appetite sensation (VAS)
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Study Design RCT-c
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Country/Region EU
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Age (mean or range) 33.5
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Age 33.5
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% Male 0.5
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BMI 31.4
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Intervention Form Beverage
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Sample size 24
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Number analyzed (intervention) 24
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Number analyzed (control) 24
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Baseline health overweight/obese
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Baseline health (coded) overweight
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Duration 3 weeks
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Duration (coded) 2 day - 1 month
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brain 1
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glycaemia 1
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appetite 1
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dietary 0
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bodyweight 0
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Primary (Most important outcome) appetite and hormone
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Hypotheses/Aim(s) of Study aim to investigate the acute effects of two energy containing drinks (sucrose sweeteneed regular cola and isocaloric semi0skimmed milk) and two non0nerergycontaining drinks (aspartame -sweetneed diet cola and water) on appetite scores, appetite regulating homrmones and EI. We hypothesize semi0skied milk would induce more satiety signals than isocaloric regular cola and diet colar would increase EI a the following meal as compared with water
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Funding source Danish council for Strategic Research, Agriculture and Fishereis, Novo Nordic Foundation, and Clinical Institute at Aarhus University, Denmark
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Funding(coded) NP
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Internal
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Results & Comparisons

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