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Study Title and Description

Sucrose-sweetened beverages increase fat storage in the liver, muscle, and visceral fat depot: a 6-mo randomized intervention study.



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title Sucrose-sweetened beverages increase fat storage in the liver, muscle, and visceral fat depot: a 6-mo randomized intervention study.
Author Maersk M, Belza A, Stødkilde-Jørgensen H, Ringgaard S, Chabanova E, Thomsen H, Pedersen SB, Astrup A, Richelsen B.
Country Department of Endocrinology and Internal Medicine MEA, Aarhus University Hospital, Denmark.
Year 2011
Numbers Pubmed ID: 22205311

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure Aspartame
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Comparator regular cola; milk; water
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LCS vs sugar/ or others 1
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Outcomes fat accumulation in VAT; ; liver; and skeletalmuscle; body weight;; composition; TG concentrations
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Study Design RCT-p
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Country/Region EU
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Age (mean or range) 20-50
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Age .
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% Male 0.36
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BMI 26-40
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Intervention Form Beverage
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Sample size 60
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Number analyzed (intervention) 47
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Number analyzed (control) 13
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Baseline health healthy
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Baseline health (coded) Healthy
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Duration 6 month
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Duration (coded) 1 - 6 months
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brain 0
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glycaemia 0
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appetite 0
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dietary 0
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bodyweight 1
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Primary (Most important outcome) body weight
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Hypotheses/Aim(s) of Study to test the hypothesis that sucrose-sweetenedcola increases ectopic fat including VAT4, total body fat accu-mulation, and metabolic risk factors in a 6-mo controlled trialcompared with 3 alternative beverages: isocaloric semiskimmilk, aspartame-sweetened cola, and water
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Funding source Danish council for Strategic Research, Agriculture and Fishereis, Novo Nordic Foundation, and Clinical Institute at Aarhus University, Denmark
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Funding(coded) NP
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Internal
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Results & Comparisons

No Results found.