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Study Title and Description

Consumption of caloric and non-caloric versions of a soft drink differentially affects brain activation during tasting.



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title Consumption of caloric and non-caloric versions of a soft drink differentially affects brain activation during tasting.
Author Smeets PA, Weijzen P, de Graaf C, Viergever MA.
Country Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands. paul@isi.uu.nl
Year 2010
Numbers Pubmed ID: 20804848

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure non-caloric artificial sweeteners
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Comparator Sucrose
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LCS vs sugar/ or others 1
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Outcomes whole brain analysis (activations); activations of: insula; oribitofrontal cortex (OFC); amygdala and striatum; sensory-specific satiety effects in the brain on taste activation; pleasantness ratings and sensory-specific satiety; Ratings of appetite and thirst
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Study Design RCT-c
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Country/Region EU
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Age (mean or range) 23.3
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Age 23.3
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% Male 1
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BMI 22.4
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Intervention Form Beverage
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Sample size 10
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Number analyzed (intervention) 10
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Number analyzed (control) 10
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Baseline health healthy
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Baseline health (coded) Healthy
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Duration 4 (separate) days
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Duration (coded) 2 day - 1 month
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brain 1
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glycaemia 0
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appetite 1
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dietary 0
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bodyweight 0
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Primary (Most important outcome) appetite
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Hypotheses/Aim(s) of Study purpose of the present study was to measure the effects of oro-sensory stimulation and energy content on taste-related brain activations.
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Funding source This study was financially partly supported by an unrestricted educational grant of the Dutch Sugar Bureau (Baarn, The Netherlands).
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Funding(coded) Government
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Internal
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Results & Comparisons

No Results found.