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Study Title and Description

Immunoreactive beta-endorphin increases after an aspartame chocolate drink in healthy human subjects.



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title Immunoreactive beta-endorphin increases after an aspartame chocolate drink in healthy human subjects.
Author Melchior JC, Rigaud D, Colas-Linhart N, Petiet A, Girard A, Apfelbaum M.
Country Laboratoire de Nutrition Humaine, Unité INSERM 286, C.H.U. Bichat, Paris, France.
Year 1991
Numbers Pubmed ID: 1805284

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure Aspartame
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Comparator Sucrose
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LCS vs sugar/ or others 1
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Outcomes Changes in:; mean plasma glucose concentrations; plasma beta endorphin concentrations; hunger ratings
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Study Design RCT-c
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Country/Region EU
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Age (mean or range) 21.7
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Age 21.7
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% Male 0.3
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BMI 20.6
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Intervention Form Beverage
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Sample size 10
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Number analyzed (intervention) 10
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Number analyzed (control) nr
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Baseline health healthy
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Baseline health (coded) Healthy
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Duration <1day3 (separate) days
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Duration (coded) <1 day
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brain 0
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glycaemia 1
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appetite 1
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dietary 0
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bodyweight 0
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Primary (Most important outcome) glycaemia
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Hypotheses/Aim(s) of Study The present work was undertaken in an attempt to discriminate between the effects of sensorial pleasure and of energy intake on the probably rise of plasma beta-endorphin concentrations after a meal
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Funding source Ministry of research and technology in the program "Aliment" 2000
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Funding(coded) Government
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Internal
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