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Study Title and Description

Comparative effects of fructose, aspartame, glucose, and water preloads on calorie and macronutrient intake.



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title Comparative effects of fructose, aspartame, glucose, and water preloads on calorie and macronutrient intake.
Author Rodin J.
Country Department of Psychology, Yale University, New Haven, CT 06520.
Year 1990
Numbers Pubmed ID: 2178391

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure Aspartame
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Comparator Glucose, Fructose
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LCS vs sugar/ or others 1
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Outcomes caloric intake; Plasma concentrations ofglucose; insulin; glucagon; and FFA; Relationship between blood concentrations of hormones or glucose and amount of food consumed
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Study Design RCT-c
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Country/Region US
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Age (mean or range) 22-50
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Age .
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% Male 0.5
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BMI NR (have % overweight)
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Intervention Form Beverage
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Sample size 24
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Number analyzed (intervention) 24
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Number analyzed (control) 24
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Baseline health half normal, half overweight
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Baseline health (coded) Mixed
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Duration 4 (separate) sessions
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Duration (coded) <1 day
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brain 0
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glycaemia 1
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appetite 0
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dietary 1
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bodyweight 0
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Primary (Most important outcome) dietary intake
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Hypotheses/Aim(s) of Study consider the effect of various sweeteners on later food intake by using a time delay that was much shorter than that used in previous studies
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Funding source NIH
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Funding(coded) Government
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Internal
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Results & Comparisons

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