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Study Title and Description

Sweet taste: effect on cephalic phase insulin release in men.



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title Sweet taste: effect on cephalic phase insulin release in men.
Author Teff KL, Devine J, Engelman K.
Country Monell Chemical Senses Center, Philadelphia, PA 19104, USA.
Year 1995
Numbers Pubmed ID: 7652029

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure Saccharin, Aspartame
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Comparator Sucrose
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LCS vs sugar/ or others 1
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Outcomes changes in insulin; glucose; net AUC; sensory ratings (pleasantness); Three Factor Eating Questionnaire results (restraint; disinhibition; and susceptibility to hunger)
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Study Design nRCT-c
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Country/Region US
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Age (mean or range) 26
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Age 26
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% Male 1
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BMI 23.3
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Intervention Form Beverage
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Sample size 16
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Number analyzed (intervention) 16
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Number analyzed (control) 16
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Baseline health healthy
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Baseline health (coded) Healthy
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Duration 5 days
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Duration (coded) 2 day - 1 month
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brain 1
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glycaemia 1
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appetite 1
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dietary 0
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bodyweight 0
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Primary (Most important outcome) glycaemia
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Hypotheses/Aim(s) of Study determine whether sweet-tasting solution are effective elicitors of cephalic phase insulin relesase (CPIR) in humans, two studieswere conducted using nutritie and nonnutritive sweeteners as stimuli
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Funding source NIH and Monnell Chemical Sciences Center
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Funding(coded) Government & NP
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Internal 7652029-2
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