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Study Title and Description

An evaluation of the effect of aspartame on weight loss.



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title An evaluation of the effect of aspartame on weight loss.
Author Kanders BS, Lavin PT, Kowalchuk MB, Greenberg I, Blackburn GL.
Country Cancer Research Institute, New England Deaconess Hospital, Boston, MA 02215.
Year 1988
Numbers Pubmed ID: 3190220

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure Aspartame
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Comparator meal
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LCS vs sugar/ or others 2
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Outcomes weight; BMI change; quality of life (pain hunger; desire for sweet; craving; thirst; nausea; feeling of well-being; mood; eating)
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Study Design RCT-p
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Country/Region US
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Age (mean or range) 20-60
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Age .
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% Male 0.22
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BMI NR
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Intervention Form Food or Meal
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Sample size 59
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Number analyzed (intervention) 28
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Number analyzed (control) 27
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Baseline health overweight/obese
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Baseline health (coded) overweight
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Duration 12 weeks
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Duration (coded) 1 - 6 months
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brain 0
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glycaemia 0
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appetite 1
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dietary 0
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bodyweight 1
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Primary (Most important outcome) weight
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Hypotheses/Aim(s) of Study This study explores whether the addition of aspartame-sweetened foods and beverages to a low fat, hypocaloric diet enhances compliance and resulting weight loss.
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Funding source NutraSwcet Company, the Center For Nutritional Research-Charitable Trust, and NIH grant
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Funding(coded) Industry
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Internal
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