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Study Title and Description

Lactitol versus lactulose in the treatment of chronic hepatic encephalopathy. A double-blind, randomised, cross-over study.



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title Lactitol versus lactulose in the treatment of chronic hepatic encephalopathy. A double-blind, randomised, cross-over study.
Author Morgan MY, Hawley KE, Stambuk D.
Country -- Not Found --
Year 1987
Numbers Pubmed ID: 3295020

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure Lactitol
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Comparator lactulose
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LCS vs sugar/ or others 2
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Outcomes clinical status; ; EEG (electro-encephalogram) frequencies; ; blood ammonia concentration; ; stool number
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Study Design RCT-c
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Country/Region EU
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Age (mean or range) NR
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Age .
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% Male NR
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BMI NR
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Intervention Form Beverage
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Sample size 12
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Number analyzed (intervention) 9
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Number analyzed (control) 0
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Baseline health patients requiring long-term treatment for chronic hepatic encephalopathy
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Baseline health (coded) Other
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Duration 6 months
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Duration (coded) 1 - 6 months
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brain 1
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glycaemia 0
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appetite 0
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dietary 0
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bodyweight 0
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Primary (Most important outcome) taste
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Hypotheses/Aim(s) of Study The efficacy of lactitol in the treatment of chronic hepatic encephalopathy was assessed in 9 cirrhotic patients in a randomised, double-blind, cross-over comparison with lactulose.
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Funding source NR
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Funding(coded) nr
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Internal
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Results & Comparisons

No Results found.