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Study Title and Description

Phenylalanine and aspartame fail to alter feeding behavior, mood and arousal in men.



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title Phenylalanine and aspartame fail to alter feeding behavior, mood and arousal in men.
Author Ryan-Harshman M, Leiter LA, Anderson GH.
Country -- Not Found --
Year 1987
Numbers Pubmed ID: 3575461

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure Aspartame (APM)
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Comparator phenylalanine (PHE)
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LCS vs sugar/ or others 2
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Outcomes (note: 2 experiments in this study; only exp 2 is relevant to us (exp 1 only looks at PHE); mean energy intake; macronutrient selection; Visual analog scales (VAS) scores: emptiness; stomach rumbling; ache; nausea; headache; dizziness; fainting; drowsiness; nervousness; tenseness; drugged; depressed; alert; mentally slow; weakness; degree of hunger and urge to eat; Values for plasma PHE; tyrosine (TYR); PHE/NAA; TYR/neutral amino acids (NAA) and tryptophan(TRP)/NAA
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Study Design RCT-c
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Country/Region CA
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Age (mean or range) 20-35
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Age .
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% Male 1
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BMI NR
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Intervention Form Sup or Oral
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Sample size 13
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Number analyzed (intervention) 13
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Number analyzed (control) 13
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Baseline health healthy
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Baseline health (coded) Healthy
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Duration 4 sessions, 1/week
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Duration (coded) <1 day
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brain 1
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glycaemia 0
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appetite 1
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dietary 1
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bodyweight 0
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Primary (Most important outcome) dietary intake
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Hypotheses/Aim(s) of Study The primary objective of this research was to measure the human behavior effects of PHE on short-term energy and macronutrient (protein, carbohydrate, fat) intakes at lunch time and on sub- jective feelings of hunger, mood and arousal in young adult males. However, a secondary objective of this research was to examine the effect of large doses of aspartame (APM) on food intake, mood and arousal of young men.
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Funding source ILSI Nutrition Foundation
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Funding(coded) NP
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Internal
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Results & Comparisons

No Results found.