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Study Title and Description

Effects of aspartame in young persons during weight reduction.



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title Effects of aspartame in young persons during weight reduction.
Author Knopp RH, Brnadt K, Arky RA
Country -- Not Found --
Year 1976
Numbers Pubmed ID: 796476

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure Aspartame
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Comparator lactose
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LCS vs sugar/ or others 1
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Outcomes body weight; blood pressure; urinary tests; plasma AA
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Study Design RCT-p
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Country/Region US
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Age (mean or range) 19.3
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Age 19.3
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% Male 0.7
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BMI NR
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Intervention Form Sup or Oral
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Sample size 59
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Number analyzed (intervention) 24
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Number analyzed (control) 33
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Baseline health healthy
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Baseline health (coded) Healthy
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Duration 13 weeks
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Duration (coded) 1 - 6 months
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brain 0
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glycaemia 0
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appetite 0
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dietary 0
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bodyweight 1
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Primary (Most important outcome) weight
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Hypotheses/Aim(s) of Study Given the potential use of a low-claorie sweetener during weight reduction, a toxicity sutdy of chronic aspartame ingestion was conducted
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Funding source Training grant from USPHS Division of Research Faciliti8es and Resources and a grant from the Searle Company
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Funding(coded) NP and Industry
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Internal
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Results & Comparisons

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