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Study Title and Description

Effect of sucrose on the metabolic disposition of aspartame.



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title Effect of sucrose on the metabolic disposition of aspartame.
Author Stegink LD, Brummel MC, Persoon TJ, Filer LJ Jr, Bell EF, Ziegler EE.
Country Department of Pediatrics, University of Iowa College of Medicine, Iowa City 52242.
Year 1990
Numbers Pubmed ID: 2197852

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure Aspartame
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Comparator Aspartame and Sucrose
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LCS vs sugar/ or others 1
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Outcomes plasma phenylalanine
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Study Design RCT-c
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Country/Region US
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Age (mean or range) nr
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Age .
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% Male 0.5
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BMI nr
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Intervention Form Beverage
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Sample size 12
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Number analyzed (intervention) 12
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Number analyzed (control) 12
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Baseline health healthy
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Baseline health (coded) Healthy
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Duration 2 days
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Duration (coded) 2 day - 1 month
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brain 0
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glycaemia 0
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appetite 0
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dietary 0
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bodyweight 0
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Primary (Most important outcome) glycaemia
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Hypotheses/Aim(s) of Study To examine the effect of carbohydrate on the metabolic distribution of APM by measuring plasma amino acid, glucose, and insulin concentrations in normal adults ingesting APM in beverage with and without sucrose
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Funding source NIH and company NutraSweet
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Funding(coded) Government and Industry
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Internal
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Results & Comparisons

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