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Study Title and Description

Reduced glycaemic and insulinaemic responses following isomaltulose ingestion: implications for postprandial substrate use.



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title Reduced glycaemic and insulinaemic responses following isomaltulose ingestion: implications for postprandial substrate use.
Author van Can JG, Ijzerman TH, van Loon LJ, Brouns F, Blaak EE.
Country Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht (NUTRIM), Maastricht University, Maastricht, The Netherlands. j.vancan@hb.unimaas.nl
Year 2009
Numbers Pubmed ID: 19671200

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure Isomaltulose
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Comparator Sucrose
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LCS vs sugar/ or others 1
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Outcomes Plasma glucose; plasma insulin; pasma non-esteriļ¬ed fatty acids and triacylglycerol; total fat oxidation rate; total carbohydrate oxidation rate; thermogenesis and respiratory quotient; Exogenous carbohydrate oxidation rates; Satiety peptides responses (ghrelin and GLP-1)
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Study Design RCT-c
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Country/Region EU
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Age (mean or range) 31
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Age 31
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% Male 0.8
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BMI 27.7
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Intervention Form Beverage
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Sample size 10
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Number analyzed (intervention) 10
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Number analyzed (control) 10
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Baseline health healthy overweight
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Baseline health (coded) overweight
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Duration 1 week
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Duration (coded) 2 day - 1 month
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brain 0
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glycaemia 1
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appetite 1
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dietary 0
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bodyweight 0
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Primary (Most important outcome) glycaemia
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Hypotheses/Aim(s) of Study
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Funding source Cargill Inc.
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Funding(coded) Industry
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Internal
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