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Study Title and Description

Postprandial substrate use in overweight subjects with the metabolic syndrome after isomaltulose (Palatinoseâ„¢) ingestion.



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title Postprandial substrate use in overweight subjects with the metabolic syndrome after isomaltulose (Palatinoseâ„¢) ingestion.
Author Konig D, Theis S, Kozianowski G, Berg A.
Country Department of Rehabilitation, Prevention and Sports Medicine, Center for Internal Medicine, University Hospital Freiburg, Freiburg, Germany. Daniel.Koenig@uniklinik-freiburg.de
Year 2012
Numbers Pubmed ID: 22264450

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure Isomaltulose
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Comparator Glucose and Sucrose
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LCS vs sugar/ or others 1
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Outcomes blood glucose; non-esterified fatty acid (NEFA) levels; TG levels; fat oxidation; carbohydrate oxidation; total energy expenditure
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Study Design RCT-c
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Country/Region EU
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Age (mean or range) 50.7
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Age 50.7
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% Male 1
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BMI 32.1
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Intervention Form Food or Meal
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Sample size 20
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Number analyzed (intervention) 20
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Number analyzed (control) 20
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Baseline health overweight/obese, other
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Baseline health (coded) overweight
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Duration < 1 day, 2 sessions
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Duration (coded) <1 day
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brain 0
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glycaemia 1
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appetite 0
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dietary 1
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bodyweight 0
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Primary (Most important outcome) glycaemia
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Hypotheses/Aim(s) of Study Study aim: investigated the postprandial metabolic response at rest and during physical activity after an intake of the low glycemic carbohydrate isomaltulose compared with a conventional carbohydrate (glucose syrup/ sucrose [glc/suc]) with a higher glycemic index.
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Funding source BENEO (member of Sudzucker Group)
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Funding(coded) Industry
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Internal
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