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Study Title and Description

Further analysis of the short-term inhibition of food intake in humans by the dipeptide L-aspartyl-L-phenylalanine methyl ester (aspartame).



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title Further analysis of the short-term inhibition of food intake in humans by the dipeptide L-aspartyl-L-phenylalanine methyl ester (aspartame).
Author Rogers PJ, Keedwell P, Blundell JE.
Country Consumer Sciences Department, AFRC Institute of Food Research, Reading, United Kingdom.
Year 1991
Numbers Pubmed ID: 1881978

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure Aspartame
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Comparator none
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LCS vs sugar/ or others 2
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Outcomes food intake; desire to eat
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Study Design RCT-c
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Country/Region UK
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Age (mean or range) 20-37
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Age .
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% Male 0.375
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BMI 22.4
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Intervention Form Beverage
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Sample size 16
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Number analyzed (intervention) 16
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Number analyzed (control) 16
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Baseline health healthy
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Baseline health (coded) Healthy
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Duration <1
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Duration (coded) <1 day
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brain 0
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glycaemia 0
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appetite 1
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dietary 1
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bodyweight 0
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Primary (Most important outcome) dietary intake
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Hypotheses/Aim(s) of Study To test that phenylalanine moiety of aspartame is responsible for postingestive inhibitory effect ono appetite
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Funding source Agrilcultural and Food Research Concil
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Funding(coded) Government
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Internal
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Results & Comparisons

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