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Study Title and Description

Response to single dose of aspartame or saccharin by NIDDM patients.



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title Response to single dose of aspartame or saccharin by NIDDM patients.
Author Horwitz DL, McLane M, Kobe P.
Country Department of Medicine, University of Illinois, Chicago 60680.
Year 1988
Numbers Pubmed ID: 3046854

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure Aspartame, Saccharin
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Comparator unsweetened beverage
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LCS vs sugar/ or others 2
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Outcomes glucose; insulin; glucagon
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Study Design RCT-c
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Country/Region US
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Age (mean or range) 42.5
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Age 42.5
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% Male 0.227
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BMI <150% ideal body weight
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Intervention Form Beverage
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Sample size 22
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Number analyzed (intervention) 22
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Number analyzed (control) 22
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Baseline health normal and NIDDM (diabetes)
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Baseline health (coded) Mixed
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Duration 3 sessions (<1 day each), separated by at least 1 week each time
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Duration (coded) <1 day
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brain 0
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glycaemia 1
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appetite 0
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dietary 0
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bodyweight 0
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Primary (Most important outcome) glycaemia
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Hypotheses/Aim(s) of Study Study aim: to determine whether aspartame alters blood lev-els of glucose, insulin, or glucagon.
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Funding source NutraSweet Company
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Funding(coded) Industry
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Internal
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Results & Comparisons

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