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Study Title and Description

Effects of an osmotically active agent on colonic transit.



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title Effects of an osmotically active agent on colonic transit.
Author Skoog SM, Bharucha AE, Camilleri M, Burton DD, Zinsmeister AR.
Country Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA.
Year 2006
Numbers Pubmed ID: 16553585

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure Sorbitol
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Comparator dextrose
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LCS vs sugar/ or others 2
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Outcomes VAS; breath hydrogen excretion
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Study Design RCT-p
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Country/Region US
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Age (mean or range) 35
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Age 35
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% Male 0.375
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BMI nr
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Intervention Form Beverage
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Sample size 40
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Number analyzed (intervention) 20
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Number analyzed (control) 20
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Baseline health healthy
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Baseline health (coded) Healthy
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Duration <1 day
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Duration (coded) <1 day
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brain 1
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glycaemia 0
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appetite 0
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dietary 0
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bodyweight 0
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Primary (Most important outcome) appetite
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Hypotheses/Aim(s) of Study sorbitol would acceleratecolonic transit in healthy subjects, and that theseeffects would be reduced by concomitant foodingestion.
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Funding source grants from NIH and general clinical research
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Funding(coded) Government
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Internal
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Results & Comparisons

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