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Study Title and Description

Novel findings on the metabolic effects of the low glycaemic carbohydrate isomaltulose (Palatinose).



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title Novel findings on the metabolic effects of the low glycaemic carbohydrate isomaltulose (Palatinose).
Author Holub I, Gostner A, Theis S, Nosek L, Kudlich T, Melcher R, Scheppach W.
Country Department of Medicine II, Division of Gastroenterology, University of Würzburg, Würzburg, Germany. holub_i@medizin.uni-wuerzburg.de
Year 2010
Numbers Pubmed ID: 20211041

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure Isomaltulose
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Comparator none
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LCS vs sugar/ or others 2
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Outcomes plasma glucose; ; plasma insulin; urine and stool ; blood lipids; C-peptide; proinsulin; fructosamine; insulin resistance
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Study Design RCT-c
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Country/Region EU
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Age (mean or range) 48.2
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Age 48.2
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% Male 0.4
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BMI nr
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Intervention Form Food or Meal
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Sample size 20
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Number analyzed (intervention) 20
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Number analyzed (control) 20
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Baseline health healthy and overweight
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Baseline health (coded) Mixed
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Duration 4 weeks
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Duration (coded) 2 day - 1 month
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brain 0
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glycaemia 1
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appetite 0
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dietary 0
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bodyweight 0
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Primary (Most important outcome) glycaemia
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Hypotheses/Aim(s) of Study (a) toinvestigate the actual availability, i.e. digestibility and absorp-tion of iso from human small intestine after consumption ofiso-rich meals; (b) to examine glucose and insulin responseto iso intake in healthy subjects; (c) to study possible healtheffects of a regular consumption of iso in volunteers withhyperlipidaemia.
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Funding source Sudzucker Group and University of Wurzburg
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Funding(coded) Industry
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Internal
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Results & Comparisons

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