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Study Title and Description

Ingestion of diet soda before a glucose load augments glucagon-like peptide-1 secretion.



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title Ingestion of diet soda before a glucose load augments glucagon-like peptide-1 secretion.
Author Brown RJ, Walter M, Rother KI.
Country National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA. brownrebecca@mail.nih.gov
Year 2009
Numbers Pubmed ID: 19808921

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure sucralose, acesulfame-k
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Comparator Carbonated water
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LCS vs sugar/ or others 2
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Outcomes glucose; insulin; GLP-1
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Study Design RCT-c
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Country/Region US
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Age (mean or range) 12-25
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Age .
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% Male 0.45
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BMI 25.6
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Intervention Form Beverage
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Sample size 22
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Number analyzed (intervention) 22
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Number analyzed (control) 22
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Baseline health healthy
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Baseline health (coded) healthy
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Duration <1 day
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Duration (coded) <1 day
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brain 0
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glycaemia 1
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appetite 0
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dietary 0
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bodyweight 0
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Primary (Most important outcome) glycaemia
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Hypotheses/Aim(s) of Study To examine the effect of artificial sweeteners in a commercially available soft drink on glucose, insulin, and GLP-1 in humans
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Funding source National Institute of Diabetes and Digestive and Kidney Diseases.
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Funding(coded) NP
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Internal
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