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Study Title and Description

A double-blind placebo-controlled study of the effectiveness and tolerability of oral stevioside in humanhypertension.



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title A double-blind placebo-controlled study of the effectiveness and tolerability of oral stevioside in humanhypertension.
Author Chan P1, Tomlinson B, Chen YJ, Liu JC, Hsieh MH, Cheng JT
Country Division of Cardiovascular Medicine, Taipei Medical College and affiliated Taipei Wan Fang Hospital, Taiwan.
Year 2000
Numbers Pubmed ID: 10971305

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure Stevioside
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Comparator placebo
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LCS vs sugar/ or others 2
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Outcomes systeolic and diastolic blood pressure; BMI; blood serum(Cr; CPK; AST; ALT; Na; K; Cl) total cholesterol; HDL; TG; glucose; quality of life
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Study Design RCT-p
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Country/Region ASIA
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Age (mean or range) 54.1
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Age 54.1
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% Male 0.57
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BMI 23
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Intervention Form Sup or Oral
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Sample size 106
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Number analyzed (intervention) 60
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Number analyzed (control) 46
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Baseline health Hypertensive
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Baseline health (coded) Other
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Duration 1 yr
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Duration (coded) >1 year
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brain 0
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glycaemia 1
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appetite 0
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dietary 0
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bodyweight 1
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Primary (Most important outcome) glycaemia
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Hypotheses/Aim(s) of Study To evaluate the tolerabilities and efficiacy of stevioside glycoside in treatment of human hypertension
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Funding source Taipei Medical College and Taipei Wan Fang Hospital
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Funding(coded) NP & Government
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Internal
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Results & Comparisons

No Results found.