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Study Title and Description

Investigation of the antihypertensive effect of oral crude stevioside in patients with mild essential hypertension.



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title Investigation of the antihypertensive effect of oral crude stevioside in patients with mild essential hypertension.
Author Ferri LA1, Alves-Do-Prado W, Yamada SS, Gazola S, Batista MR, Bazotte RB.
Country Programa de Pós Graduação em Ciências Farmacêuticas, UEM, Universidade Estadual de Maringá, Maringá, Av Colombo, PR, Brazil.
Year 2006
Numbers Pubmed ID: 16775813

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure stevioside
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Comparator placebo
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LCS vs sugar/ or others 2
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Outcomes blood pressure; BMI; cholesterol; HDL; LDL; VLDL; TG; glucose; insulin; hemoglobin
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Study Design RCT-p
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Country/Region Africa
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Age (mean or range) 45
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Age 45
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% Male 0.14
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BMI 26
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Intervention Form Sup or Oral
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Sample size 14
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Number analyzed (intervention) 7
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Number analyzed (control) 7
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Baseline health Hypertensive
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Baseline health (coded) Other
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Duration 24 weeks
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Duration (coded) 1 - 6 months
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brain 0
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glycaemia 0
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appetite 0
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dietary 0
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bodyweight 1
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Primary (Most important outcome) weight
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Hypotheses/Aim(s) of Study To evaluate the antihypertensive potential of oral crude stevioside obtained from leaves of stevia rebaudiana Bertoni cultivated in northeastern Paraguay and southern Brazil
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Funding source CNPq grant
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Funding(coded) Government
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Internal
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Results & Comparisons

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