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Study Title and Description

Increased postprandial glycaemia, insulinemia, and lipidemia after 10 weeks' sucrose-rich diet compared to anartificially sweetened diet: a randomised controlled trial.



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title Increased postprandial glycaemia, insulinemia, and lipidemia after 10 weeks' sucrose-rich diet compared to anartificially sweetened diet: a randomised controlled trial.
Author Raben A1, Møller BK, Flint A, Vasilaris TH, Christina Møller A, Juul Holst J, Astrup A.
Country Department of Human Nutrition, Faculty of LIFE sciences, University of Copenhagen, DK.
Year 2011
Numbers Pubmed ID: 21799667

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure artificially sweetened beverages (LCS not specified)
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Comparator sucrose
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LCS vs sugar/ or others 1
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Outcomes glucose; insulin; lactate; TG; leptin; glucagon; GLP-1; body weight; GIP; energy intake; sugar intake
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Study Design RCT-P
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Country/Region
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Age (mean or range) 35
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Age 35
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% Male NA
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BMI 28
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Intervention Form Sup or Oral
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Sample size 23
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Number analyzed (intervention) 11
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Number analyzed (control) 12
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Baseline health overweight
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Baseline health (coded) overweight
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Duration 10 weeks
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Duration (coded) 1 - 6 months
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brain 0
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glycaemia 1
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appetite 0
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dietary 1
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bodyweight 1
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Primary (Most important outcome) glycaemia
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Hypotheses/Aim(s) of Study To investigate the effects of a diet high in sucrose versus a diet high in artificial sweeteners on fasting and postprandial metabolic profiles after 10 weeks.
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Funding source The Danish Research Councils, FØTEK (Developement Programme for Food Technology), and Danisco Sugar.
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Funding(coded) NP & Industry
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Internal
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