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Study Title and Description

Aspartame-sweetened beverage: effect on plasma amino acid concentrations in normal Adults and Adults heterozygous for phenylketonuria.2



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title Aspartame-sweetened beverage: effect on plasma amino acid concentrations in normal Adults and Adults heterozygous for phenylketonuria.2
Author Stegink LD, Wolf-Novak LC, Filer LJ Jr, Bell EF, Ziegler EE, Krause WL, Brummel MC.2
Country
Year 1987
Numbers

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure Aspartame
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Comparator kool-aid
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LCS vs sugar/ or others 1
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Outcomes plasma TYR; ASP; PHE; LNAA
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Study Design RCT-c
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Country/Region US
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Age (mean or range) nr
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Age .
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% Male 0.5
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BMI nr
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Intervention Form Beverage
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Sample size 14
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Number analyzed (intervention) 14
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Number analyzed (control) nr
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Baseline health mix of health and six obligate phenylketonuric (PKU) heterozygous Adults
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Baseline health (coded) Mixed
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Duration <1day
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Duration (coded) <1 day
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brain 0
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glycaemia 0
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appetite 0
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dietary 0
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bodyweight 0
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Primary (Most important outcome) glycaemia
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Hypotheses/Aim(s) of Study
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Funding source G. D. Searle, Skokie, IL
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Funding(coded) Industry
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