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Study Title and Description

Molecular mechanism of sweet taste: relationship of hydrogen bonding to taste sensitivity for both young and elderly.2



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title Molecular mechanism of sweet taste: relationship of hydrogen bonding to taste sensitivity for both young and elderly.2
Author Schiffman SS, Lindley MG, Clark TB, Makino C.2
Country
Year 1981
Numbers

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure - Acetosulfam- Aspartame- rebaudioside A- Saccharin (sodium salt)- stevioside- thaumatin- Neohesperidin dihydrochalcone
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Comparator - Fructose,- monellin,- D-tryptophan,- Ca cyclamate
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LCS vs sugar/ or others 1
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Outcomes magnitude estimation: concentration and perceived intensity among young vs elderly subjects
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Study Design RCT-c
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Country/Region US
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Age (mean or range) 21-77
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Age .
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% Male 0.17
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BMI nr
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Intervention Form Beverage
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Sample size 24
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Number analyzed (intervention) nr
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Number analyzed (control) nr
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Baseline health healthy
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Baseline health (coded) Healthy
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Duration < 1 day
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Duration (coded) <1 day
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brain 1
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glycaemia 0
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appetite 0
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dietary 0
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bodyweight 0
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Primary (Most important outcome) taste
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Hypotheses/Aim(s) of Study The purpose of this study was to investigate the possible molecular mechanisms underlying the sensation of sweetness for young and elderly subjects using both threshold measurements and psychophysical functions reflecting the growth of perceived intensity with concentration.
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Funding source NIA
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Funding(coded) NP
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Results & Comparisons

No Results found.