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Study Title and Description

Sweet taste: effect on cephalic phase insulin release in men.1



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title Sweet taste: effect on cephalic phase insulin release in men.1
Author Teff KL, Devine J, Engelman K.1
Country
Year 1995
Numbers

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure Saccharin, Aspartame
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Comparator Sucrose
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LCS vs sugar/ or others 1
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Outcomes changes in insulin; glucose; net AUC; sensory ratings (pleasantness); Three Factor Eating Questionnaire results (restraint; disinhibition; and susceptibility to hunger)
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Study Design nRCT-c
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Country/Region US
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Age (mean or range) 25
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Age 25
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% Male 1
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BMI 22.8
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Intervention Form Beverage
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Sample size 15
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Number analyzed (intervention) 15
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Number analyzed (control) 15
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Baseline health healthy
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Baseline health (coded) Healthy
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Duration 5 days
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Duration (coded) 2 day - 1 month
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brain 1
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glycaemia 1
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appetite 1
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dietary 0
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bodyweight 0
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Primary (Most important outcome) glycaemia
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Hypotheses/Aim(s) of Study determine whether sweet-tasting solution are effective elicitors of cephalic phase insulin relesase (CPIR) in humans, two studieswere conducted using nutritie and nonnutritive sweeteners as stimuli
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Funding source NIH and Monnell Chemical Sciences Center
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Funding(coded) Government & NP
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