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Study Title and Description

Cephalic phase metabolic responses in normal weight Adults.1



Key Questions Addressed
1 What are the association between low-calorie sweeteners and health?
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Primary Publication Information
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TitleData
Title Cephalic phase metabolic responses in normal weight Adults.1
Author Bruce DG, Storlien LH, Furler SM, Chisholm DJ.1
Country
Year 1987
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Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: LCS-RCT
Design Details
Question... Follow Up Answer Follow-up Answer
Population Adults
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Intervention/Exposure Aspartame
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Comparator none
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LCS vs sugar/ or others 2
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Outcomes food taste; hunger; blood glucose level; serum insulin levels; c-peptide levels; hPP
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Study Design RCT-p
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Country/Region AU
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Age (mean or range) 19-32
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Age .
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% Male 1
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BMI NR
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Intervention Form Food or Meal
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Sample size 7
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Number analyzed (intervention)
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Number analyzed (control)
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Baseline health healthy
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Baseline health (coded) Healthy
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Duration NR; either 1 or 2 <1day sessions per study
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Duration (coded) <1 day
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brain 0
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glycaemia 1
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appetite 1
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dietary 0
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bodyweight 0
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Primary (Most important outcome) glycaemia
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Hypotheses/Aim(s) of Study The aim of these studies was to determine whether cephalic phase insulin release could be demonstrated in normal weight subjects and whether it would be associated with changes in blood glucose, free fatty acid, and pancreatic polypeptide levels.
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Funding source Supported by grants from the NH and MRC (Australia). D.G. Bruce is the recipient of a CSL-Novo Scholarship.
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Funding(coded) Government
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