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Study Title and Description

Clinical outcomes of renal transplantation using liquid chromatographic monitoring of tacrolimus.



Key Questions Addressed
1 In adult renal transplants, how do liquid chromatographic and mass spectrometric analytical techniques compare with immunoassay analysis for therapeutic monitoring of full dosing regimens of the calcineurin inhibitors (CNIs) cyclosporine and tacrolimus? AND In adult renal transplants, how do liquid chromatographic and mass spectrometric analytical techniques compare with immunoassay analysis for therapeutic monitoring of lower CNI doses used in minimization, conversion, or withdrawal strategies?
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Primary Publication Information
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TitleData
Title Clinical outcomes of renal transplantation using liquid chromatographic monitoring of tacrolimus.
Author Borrows R., Chusney G., Loucaidou M., James A., Stichbury J., Van Tromp J., Cairns T., Griffith M., Hakim N., McLean A., Palmer A., Papalois V., Taube D.
Country Renal and Transplant Units, St. Mary's Hospital, Paddington, London W2 1NY, United Kingdom. richardborrows@doctors.org.uk
Year 2006
Numbers Pubmed ID: 16628143

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Therapeutic Monitoring
Arms
Number Title Description Comments
1 HPLC-MS
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2 MEIA
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Design Details
Question... Follow Up Answer Follow-up Answer
STUDY DESIGN Randomized controlled trial
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Results & Comparisons

No Results found.