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Study Title and Description

Evaluation of four automated methods for determination of whole blood cyclosporine concentrations.



Key Questions Addressed
1 In adult renal transplants, how do liquid chromatographic and mass spectrometric analytical techniques compare with immunoassay analysis for therapeutic monitoring of full dosing regimens of the calcineurin inhibitors (CNIs) cyclosporine and tacrolimus? AND In adult renal transplants, how do liquid chromatographic and mass spectrometric analytical techniques compare with immunoassay analysis for therapeutic monitoring of lower CNI doses used in minimization, conversion, or withdrawal strategies?
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Primary Publication Information
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TitleData
Title Evaluation of four automated methods for determination of whole blood cyclosporine concentrations.
Author Hamwi A., Veitl M., Männer G., Ruzicka K., Schweiger C., Szekeres T.
Country Clinical Institute for Medical and Chemical Laboratory Diagnostics, General Hospital of Vienna, University of Vienna Medical School, Austria.
Year 1999
Numbers Pubmed ID: 10478141
1073 (internal)

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Therapeutic Monitoring
Arms
Number Title Description Comments
1 HPLC-MS
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2 FPIA/AxSYM
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3 CEDIA
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4 modified EMIT
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Design Details
Question... Follow Up Answer Follow-up Answer
STUDY DESIGN Prospective comparison of analytical performance
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Results & Comparisons

No Results found.