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Study Title and Description

Cyclosporin whole blood immunoassays (AxSYM, CEDIA, and Emit): a critical overview of performance characteristics and comparison with HPLC.



Key Questions Addressed
1 In adult renal transplants, how do liquid chromatographic and mass spectrometric analytical techniques compare with immunoassay analysis for therapeutic monitoring of full dosing regimens of the calcineurin inhibitors (CNIs) cyclosporine and tacrolimus? AND In adult renal transplants, how do liquid chromatographic and mass spectrometric analytical techniques compare with immunoassay analysis for therapeutic monitoring of lower CNI doses used in minimization, conversion, or withdrawal strategies?
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Primary Publication Information
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TitleData
Title Cyclosporin whole blood immunoassays (AxSYM, CEDIA, and Emit): a critical overview of performance characteristics and comparison with HPLC.
Author Schütz E., Svinarov D., Shipkova M., Niedmann PD., Armstrong VW., Wieland E., Oellerich M.
Country Abteilung Klinische Chemie, Georg-August-Universität Göttingen, Germany. eschuetz@med.uni-goettingen.de
Year 1998
Numbers Pubmed ID: 9761250
1092 (internal)

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Therapeutic Monitoring
Arms
Number Title Description Comments
1 HPLC-MS
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2 FPIA/AxSYM
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3 CEDIA
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4 modified EMIT
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Design Details
Question... Follow Up Answer Follow-up Answer




Results & Comparisons

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