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Project: Fructose Consumption and Non-alcoholic Fatty Liver Disease (NAFLD)

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Associated Extraction Forms

Title Created by Key Questions Addressed Form Notes
Fructose and NAFLD SRDR Administrator 1, 2
Intervention Studies Quality SRDR Administrator 3
Cohort, Case Control, Single Arm Quality SRDR Administrator 4
Case Control & Cross Sectional Quality SRDR Administrator 5

Associated Studies (each link opens a new tab)

Title Author Year
Volynets et al. 2012
Sucrose-sweetened beverages increase fat storage in the liver, muscle, and visceral fat depot: a 6-mo randomized intervention study. Maersk M., Belza A., Stødkilde-Jørgensen H., Ringgaard S., Chabanova E., Thomsen H., Pedersen SB., Astrup A., Richelsen B. 2012
Cholesterol synthesis is associated with hepatic lipid content and dependent on fructose/glucose intake in healthy humans Silbernagel et al. 2012
Low to moderate sugar-sweetened beverage consumption impairs glucose and lipid metabolism and promotes inflammation in healthy young men: a randomized controlled trial Aeberli et al. 2011
Increased hepatic fat in overweight Hispanic youth influenced by interaction between genetic variation in PNPLA3 and high dietary carbohydrate and sugar consumption Davis et al. 2010
Effects of short-term overfeeding with fructose, fat and fructose plus fat on plasma and hepatic lipids in healthy men Sobrecases et al. 2010
Dietary and physical activity patterns in children with fatty liver Mager et al. 2010
Excessive fructose intake induces the features of metabolic syndrome in healthy adult men: role of uric acid in the hypertensive response Perez-Polo et al. 2010
Effects of a short-term overfeeding with fructose or glucose in healthy young males Ngo Sock et al. 2010
Fructose and oxidized low-density lipoprotein in pediatric nonalcoholic fatty liver disease: a pilot study Vos et al. 2009
Fructose overconsumption causes dyslipidemia and ectopic lipid deposition in healthy subjects with and without a family history of type 2 diabetes. Lê KA., Ith M., Kreis R., Faeh D., Bortolotti M., Tran C., Boesch C., Tappy L. 2009
Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans. Stanhope KL., Schwarz JM., Keim NL., Griffen SC., Bremer AA., Graham JL., Hatcher B., Cox CL., Dyachenko A., Zhang W., McGahan JP., Seibert A., Krauss RM., Chiu S., Schaefer EJ., Ai M., Otokozawa S., Nakajima K., Nakano T., Beysen C., Hellerstein MK., Berglund L., Havel PJ. 2009
Nonalcoholic fatty liver disease in humans is associated with increased plasma endotoxin and plasminogen activator inhibitor 1 concentrations and with fructose intake. Thuy S., Ladurner R., Volynets V., Wagner S., Strahl S., Königsrainer A., Maier KP., Bischoff SC., Bergheim I. 2008
Fructose consumption as a risk factor for non-alcoholic fatty liver disease. Ouyang X., Cirillo P., Sautin Y., McCall S., Bruchette JL., Diehl AM., Johnson RJ., Abdelmalek MF. 2008
Markedly blunted metabolic effects of fructose in healthy young female subjects compared with male subjects. Couchepin C., Lê KA., Bortolotti M., da Encarnaçao JA., Oboni JB., Tran C., Schneiter P., Tappy L. 2008
A 4-wk high-fructose diet alters lipid metabolism without affecting insulin sensitivity or ectopic lipids in healthy humans. Lê KA., Faeh D., Stettler R., Ith M., Kreis R., Vermathen P., Boesch C., Ravussin E., Tappy L. 2006
Effect of fructose overfeeding and fish oil administration on hepatic de novo lipogenesis and insulin sensitivity in healthy men. Faeh D., Minehira K., Schwarz JM., Periasamy R., Periasami R., Park S., Seongsu P., Tappy L. 2005
The influence of diet upon liver function tests and serum lipids in healthy male volunteers resident in a Phase I unit. Purkins L., Love ER., Eve MD., Wooldridge CL., Cowan C., Smart TS., Johnson PJ., Rapeport WG. 2004
Effects of daily consumption of honey solution on hematological indices and blood levels of minerals and enzymes in normal individuals. Al-Waili NS. 2003
Effects of fructose feeding on blood parameters and blood pressure in impaired glucose-tolerant subjects. Koh ET., Ard NF., Mendoza F. 1988
Diet-induced changes in serum transaminase and triglyceride levels in healthy adult men. Role of sucrose and excess calories. Porikos KP., Van Itallie TB. 1983
Diets high in glucose or sucrose and young women. Kelsay JL., Behall KM., Holden JM., Prather ES. 1974
Effects of supplementation with essential amino acids on intrahepatic lipid concentrations during fructose overfeeding in humans. Theytaz F., Noguchi Y., Egli L., Campos V., Buehler T., Hodson L., Patterson BW., Nishikata N., Kreis R., Mittendorfer B., Fielding B., Boesch C., Tappy L. 2012

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