Study Preview
Study Title and Description
Effects of daily consumption of honey solution on hematological indices and blood levels of minerals and enzymes in normal individuals.
Key Questions Addressed
2 | What are the relationships between fructose consumption and indices of liver health? | |
4 | Risk of Bias - Cohort, Case-Control, and Single Arm Studies |
Primary Publication Information
Title | Effects of daily consumption of honey solution on hematological indices and blood levels of minerals and enzymes in normal individuals. |
Author | Al-Waili NS. |
Country | Dubai Specialized Medical Center and Medical Research Laboratories, Islamic Establishment for Education, Dubai, United Arab Emirates. noori786@yahoo.com |
Year | 2003 |
Numbers |
Pubmed ID: 12935325 1348 (internal) |
Secondary Publication Information
There are currently no secondary publications defined for this study.
Extraction Form: Fructose and NAFLD
Arms
Number | Title | Description | Comments |
---|---|---|---|
1 | Honey | 38% Fructose |
Design Details
Question... Follow Up | Answer | Follow-up Answer | |
---|---|---|---|
Study Design | Single Arm Trial | ||
Enrollment Years | 4 week trial | ||
Trial or Cohort Name | nd | ||
Funding Source | nd | ||
Inclusion Criteria | -normal, healthy volunteer (medical staff including doctors, nurses, and laboratory technicians) -no signs or symptoms of any diseases | ||
Exclusion Criteria | nd | ||
Location | United Arab Emirates | ||
Counfounders | No (Skip question #10) |
Baseline Characteristics
Question | Honey | Total | Comments | ||
---|---|---|---|---|---|
Answer | Follow-up | Answer | Follow-up | ||
N Enrolled | 10 | ||||
N Analyzed | 10 | ||||
Mean (SD) Age, yrs | 31.2 | ||||
Age range (IQR) | 20-45 | ||||
Male % | 70 | ||||
Anthropometry data | No data entered. | ||||
Alcohol Intake | nd | ||||
Co-morbidity (other diseases/conditions) | none | ||||
Other important baseline characteristics or baseline confounders | nd | ||||
Background Diet | "regular diet" (control) | ||||
nd | |||||
nd | |||||
nd | |||||
nd | |||||
Race/Ethnicity | nd |
Results & Comparisons
Results Data
Outcome: ALT Population: All Participants | ||
---|---|---|
Time Point | Measure | Honey |
0 N/A |
N Analyzed | 10 |
Unit | IU/L | |
Baseline Value | 27.1 | |
Baseline Standard Deviation | 17.0 | |
Final Value | 22.9 | |
Final Standard Deviation | 19.48 | |
Net Difference | -4.2 | |
Net Difference 95% Confidence Interval | nd | |
P value | 0.1223 |
Outcome: AST Population: All Participants | ||
---|---|---|
Time Point | Measure | Honey |
0 N/A |
N Analyzed | 10 |
Unit | IU/L | |
Baseline Value | 17.8 | |
Baseline Standard Deviation | 6.73 | |
Final Value | 13.9 | |
Final Standard Deviation | 8.27 | |
Net Difference | -3.9 | |
Net Difference 95% Confidence Interval | nd | |
P value | 0.0046 |
Outcome: ALP Population: All Participants | ||
---|---|---|
Time Point | Measure | Honey |
0 N/A |
N Analyzed | 10 |
Unit | IU/L | |
Baseline Value | 125 | |
Baseline Standard Deviation | 49.13 | |
Final Value | 119.7 | |
Final Standard Deviation | 41.3 | |
Net Difference | -5.3 | |
Net Difference 95% Confidence Interval | nd | |
P value | 0.8308 |
Adverse Events
Arm or Total | Title | Description | Comments |
---|---|---|---|
Honey | Not Reported | ||
Total |
Extraction Form: Cohort, Case Control, Single Arm Quality
Results & Comparisons
Results Data
Outcome: ALT Population: All Participants | ||
---|---|---|
Time Point | Measure | Honey |
0 N/A |
N Analyzed | 10 |
Unit | IU/L | |
Baseline Value | 27.1 | |
Baseline Standard Deviation | 17.0 | |
Final Value | 22.9 | |
Final Standard Deviation | 19.48 | |
Net Difference | -4.2 | |
Net Difference 95% Confidence Interval | nd | |
P value | 0.1223 |
Outcome: AST Population: All Participants | ||
---|---|---|
Time Point | Measure | Honey |
0 N/A |
N Analyzed | 10 |
Unit | IU/L | |
Baseline Value | 17.8 | |
Baseline Standard Deviation | 6.73 | |
Final Value | 13.9 | |
Final Standard Deviation | 8.27 | |
Net Difference | -3.9 | |
Net Difference 95% Confidence Interval | nd | |
P value | 0.0046 |
Outcome: ALP Population: All Participants | ||
---|---|---|
Time Point | Measure | Honey |
0 N/A |
N Analyzed | 10 |
Unit | IU/L | |
Baseline Value | 125 | |
Baseline Standard Deviation | 49.13 | |
Final Value | 119.7 | |
Final Standard Deviation | 41.3 | |
Net Difference | -5.3 | |
Net Difference 95% Confidence Interval | nd | |
P value | 0.8308 |
Quality Dimensions
Dimension | Value | Notes | Comments |
---|---|---|---|
1) Representativeness of the exposed cohort. | b | ||
2) Ascertainment of nutrient exposure | c | ||
3) Demonstration that outcome of interest was not present at start of the study | a | ||
4) Description of a validated method to quantify the amount, per type, of nutrient of interest | c | ||
5) Assessment of outcome | d | ||
6) Was follow up long enough for outcomes to occur? | a | ||
7) Adequacy of follow up of cohort | a | ||
8) Analytic control for confounding (ANY confounders other than age and sex) | a | ||
9) Analytic control for confounding: anthropomentrics | b | ||
10) Analytic control for confounding: other nutrients | b | ||
11) Power calculation to support sample size | No |
Quality Rating
Guideline Used | Overall Rating |
---|---|
Medium |