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Study Title and Description

Comparison of GenomEra C. difficile and Xpert C. difficile as confirmatory tests in a multistep algorithm for diagnosis of Clostridium difficile infection.



Key Questions Addressed
1 How do different methods for detection of toxigenic C. difficile to assist with diagnosis of CDI compare in their sensitivity, specificity, and predictive values? a. Overall? b. Do performance measures vary with sample characteristics? c. Does testing strategy impact patient health or health system outcomes?
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2 What are effective prevention strategies? a. What is the effectiveness of current prevention strategies? b. What are the harms associated with prevention strategies? c. How sustainable are prevention practices in health care (outpatient, hospital inpatient, extended care) and community settings?
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3 What is the comparative effectiveness and harms of different antibiotic treatments? a. Does effectiveness vary by disease severity?
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4 What are the effectiveness and harms of other interventions? a. Overall b. In patients with relapse/recurrent CDI.
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Primary Publication Information
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TitleData
Title Comparison of GenomEra C. difficile and Xpert C. difficile as confirmatory tests in a multistep algorithm for diagnosis of Clostridium difficile infection.
Author Alcalá L., Reigadas E., Marín M., Fernández-Chico A., Catalán P., Bouza E.
Country Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid, Spain Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES CB06/06/0058), Madrid, Spain luisalcala@efd.net.
Year 2015
Numbers Pubmed ID: 25392360

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Detection, prevention, treatments, and efficacy and harms of interventions for C. difficile


Results & Comparisons

No Results found.