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Study Title and Description

Oral, capsulized, frozen fecal microbiota transplantation for relapsing Clostridium difficile infection.



Key Questions Addressed
1 How do different methods for detection of toxigenic C. difficile to assist with diagnosis of CDI compare in their sensitivity, specificity, and predictive values? a. Overall? b. Do performance measures vary with sample characteristics? c. Does testing strategy impact patient health or health system outcomes?
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2 What are effective prevention strategies? a. What is the effectiveness of current prevention strategies? b. What are the harms associated with prevention strategies? c. How sustainable are prevention practices in health care (outpatient, hospital inpatient, extended care) and community settings?
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3 What is the comparative effectiveness and harms of different antibiotic treatments? a. Does effectiveness vary by disease severity?
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4 What are the effectiveness and harms of other interventions? a. Overall b. In patients with relapse/recurrent CDI.
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Primary Publication Information
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TitleData
Title Oral, capsulized, frozen fecal microbiota transplantation for relapsing Clostridium difficile infection.
Author Youngster I., Russell GH., Pindar C., Ziv-Baran T., Sauk J., Hohmann EL.
Country Division of Infectious Diseases, Massachusetts General Hospital, Boston2Harvard Medical School, Boston, Massachusetts3Division of Infectious Diseases, Boston Children's Hospital, Boston, Massachusetts.
Year 2014
Numbers Pubmed ID: 25322359

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Detection, prevention, treatments, and efficacy and harms of interventions for C. difficile


Results & Comparisons

No Results found.