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Study Title and Description

The potential use of cholestyramine to reduce the risk of developing Clostridium difficile-associated diarrhoea in patients receiving long-term intravenous ceftriaxone.



Key Questions Addressed
1 How do different methods for detection of toxigenic C. difficile to assist with diagnosis of CDI compare in their sensitivity, specificity, and predictive values? a. Overall? b. Do performance measures vary with sample characteristics? c. Does testing strategy impact patient health or health system outcomes?
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2 What are effective prevention strategies? a. What is the effectiveness of current prevention strategies? b. What are the harms associated with prevention strategies? c. How sustainable are prevention practices in health care (outpatient, hospital inpatient, extended care) and community settings?
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3 What is the comparative effectiveness and harms of different antibiotic treatments? a. Does effectiveness vary by disease severity?
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4 What are the effectiveness and harms of other interventions? a. Overall b. In patients with relapse/recurrent CDI.
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Primary Publication Information
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TitleData
Title The potential use of cholestyramine to reduce the risk of developing Clostridium difficile-associated diarrhoea in patients receiving long-term intravenous ceftriaxone.
Author Puri BK., Hakkarainen-Smith JS., Monro JA.
Country Department of Medicine, Hammersmith Hospital, Imperial College London, UK. Electronic address: basant.puri@imperial.ac.uk.
Year 2015
Numbers Pubmed ID: 25497389

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Detection, prevention, treatments, and efficacy and harms of interventions for C. difficile


Results & Comparisons

No Results found.