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Completed Systematic Reviews




Interventions for Substance Use Disorders in Adolescents: A Systematic Review


Public Project Complete

Statistics: 118 Studies, 1 Key Question, 1 Extraction Form,
Date Published: Jan 28, 2020 09:22PM
Description: The review aims to inform health care providers, policymakers, and a clinical practice guideline update from the American Academy of Child and Adolescent Psychiatry (AACAP) about the currently available evidence on interventions for adolescents to reduce or cease substance use. The review addresses both behavioral and pharmacological interventions used for adolescents or young adults with problematic substance use or a diagnosis of a substance use disorder (SUD), excluding tobacco.
Contributor(s): Dale W. Steele, Sara J. Becker, Kristin J. Danko, Ethan M. Balk, Ian J. Saldanha, Gaelen P. Adam, Sarah M. Bagley, Catherine Friedman. Anthony Spirito, Kelli Scott, Evangelia E. Ntzani, Iman Saeed, Bryant Smith, Jonah Popp, Thomas A. Trikalinos
DOI: DOI pending.
Funding Source: HHSA 290-2015-00002-I
Methodology Description: We conducted literature searches in MEDLINE, the Cochrane CENTRAL Trials Registry, Embase, CINAHL, and PsycINFO databases (all from inception) to identify primary studies meeting our criteria through April 11, 2019. As a part of an independent methods project, an interim search of MEDLINE was undertaken using text mining tools on October 30, 2018. A separate search for SRs of interventions for alcohol disorders/problematic alcohol use in the college setting was conducted in MEDLINE, Cochrane Database of Systematic Reviews, and Epistemonikos also through April 11, 2019; after discussion with the Technical Expert Panel (TEP), it was decided to restrict the review of this topic to existing SRs because the literature is vast and has been extensively reviewed. The literature search yielded 33,272 citations. We found 118 randomized controlled trials that evaluated treatment of adolescents or young adults with problematic substance use or substance use disorders.

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Impact of Community Health Worker Certification on Workforce and Service Delivery for Asthma and Other Selected Chronic Conditions


Public Project Complete

Statistics: 74 Studies, 2 Key Questions, 2 Extraction Forms,
Date Published: Jan 10, 2020 03:37PM
Description: Technical brief
Contributor(s): Wilson, McArthur, Ibe, Brodine
DOI: DOI pending.
Funding Source: AHRQ
Methodology Description: None Provided

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Achieving Health Equity in Preventive Services


Public Project Complete

Statistics: 85 Studies, 5 Key Questions, 1 Extraction Form,
Date Published: Dec 18, 2019 03:34PM
Description: To summarize research on achieving health equity in ten preventive services for cancer, cardiovascular disease, and diabetes in adults for a National Institutes of Health Pathways to Prevention Workshop by identifying the effects of impediments and barriers that create disparities and the effectiveness of interventions to reduce them.
Contributor(s): Heidi D. Nelson, M.D., M.P.H., M.A.C.P., F.R.C.P. Amy Cantor, M.D., M.P.H. Jesse Wagner, M.A. Rebecca Jungbauer, Dr.P.H., M.P.H, M.A. Ana QuiƱones, Ph.D., M.S. Rongwei Fu, Ph.D. Lucy Stillman, B.S. Karli Kondo, Ph.D., M.A
DOI: DOI pending.
Funding Source: AHRQ Contract No. HHSA2902015000091
Methodology Description: Eligible abstracts and full-text articles were independently dual-reviewed for inclusion using pre-established criteria. Data were abstracted into evidence tables and verified for accuracy and completeness. Risk of bias and applicability of studies were independently dual-rated using established criteria; disagreements were resolved by consensus. Strength of evidence and applicability for each Key Question and outcome were assessed through consensus using established methods. A profile likelihood random effects model was used for meta-analysis.

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Systematic reviews on interventions for corneal disease: What is the reliability of the evidence?


Public Project Complete

Statistics: 254 Studies, 1 Key Question, 1 Extraction Form,
Date Published: Nov 13, 2019 03:49PM
Description: Although a number of systematic reviews on corneal disease have been published, the reliability of these reviews remains unclear. We will characterize and appraise the methodological reliability of systematic reviews on interventions for corneal disease. The purpose of our study is to evaluate the current available evidence on interventions for corneal disease, state the strengths and limitations and formulate recommendations for improving future review conduct.
Contributor(s): None Provided
Funding Source: National Eye Institute
Methodology Description: None Provided

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Dry Eye SRs


Public Project Complete

Statistics: 40 Studies, 1 Key Question, 1 Extraction Form,
Date Published: Nov 13, 2019 03:48PM
Description: Although a number of systematic reviews on dry eye have been published, the quality of these reviews remains unclear. We will characterize and appraise the methodological quality of systematic reviews on interventions for dry eye. The purpose of our study is to evaluate the current available evidence on interventions for dry eye, state the strengths and limitations and formulate recommendations for improving future review conduct.
Contributor(s): None Provided
Funding Source: National Eye Institute
Methodology Description: None Provided

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